Table Stuck and MYSQL Hang when run table optimize table (no replies)

Hello

We have a table with almost 100000 records and have 36 fields in table

When i run OPTIMIZE TABLE MYTABLE then process just going on and after few seconds mysql also hang. Even in WHM when i try to restart mysql then it hang and we need to reboot the server

can anyone help me to solve the issue

Please note: This table work with lots of insert , select and delete queries